Publications
Clemmensen, C., S. Jall, M. Kleinert, C. Quarta, T. Gruber, J. Reber, S. Sachs, K. Fischer, A. Feuchtinger, A. Karlas, S. E. Simonds, G. Grandl, D. Loher, E. Sanchez-Quant, S. Keipert, M. Jastroch, S. M. Hofmann, E. B. M. Nascimento, P. Schrauwen, V. Ntziachristos, M. A. Cowley, B. Finan, T. D. Müller, and M. H. Tschöp. "Coordinated Targeting of Cold and Nicotinic Receptors Synergistically Improves Obesity and Type 2 Diabetes." Nat Commun 9, no. 1 (Oct 23 2018): 4304. http://dx.doi.org/10.1038/s41467-018-06769-y.
Huang, S., A. Blutke, A. Feuchtinger, U. Klemm, R. Zachariah Tom, S. M. Hofmann, A. C. Stiel, and V. Ntziachristos. "Functional Multispectral Optoacoustic Tomography Imaging of Hepatic Steatosis Development in Mice." EMBO Mol Med 13, no. 9 (Sep 7 2021): e13490. http://dx.doi.org/10.15252/emmm.202013490.
Keuper, M., L. Berti, B. Raedle, S. Sachs, A. Böhm, L. Fritsche, A. Fritsche, H. U. Häring, M. Hrabě de Angelis, M. Jastroch, S. M. Hofmann, and H. Staiger. "Preadipocytes of Obese Humans Display Gender-Specific Bioenergetic Responses to Glucose and Insulin." Mol Metab 20 (Feb 2019): 28-37. http://dx.doi.org/10.1016/j.molmet.2018.11.006.
Keuper, M., S. Sachs, E. Walheim, L. Berti, B. Raedle, D. Tews, P. Fischer-Posovszky, M. Wabitsch, M. Hrabě de Angelis, G. Kastenmüller, M. H. Tschöp, M. Jastroch, H. Staiger, and S. M. Hofmann. "Activated Macrophages Control Human Adipocyte Mitochondrial Bioenergetics Via Secreted Factors." Mol Metab 6, no. 10 (Oct 2017): 1226-39. http://dx.doi.org/10.1016/j.molmet.2017.07.008.
Lehti, M., E. Donelan, W. Abplanalp, O. Al-Massadi, K. M. Habegger, J. Weber, C. Ress, J. Mansfeld, S. Somvanshi, C. Trivedi, M. Keuper, T. Ograjsek, C. Striese, S. Cucuruz, P. T. Pfluger, R. Krishna, S. M. Gordon, R. A. Silva, S. Luquet, J. Castel, S. Martinez, D. D'Alessio, W. S. Davidson, and S. M. Hofmann. "High-Density Lipoprotein Maintains Skeletal Muscle Function by Modulating Cellular Respiration in Mice." Circulation 128, no. 22 (Nov 26 2013): 2364-71. http://dx.doi.org/10.1161/circulationaha.113.001551.
Niu, L., P. E. Geyer, N. J. Wewer Albrechtsen, L. L. Gluud, A. Santos, S. Doll, P. V. Treit, J. J. Holst, F. K. Knop, T. Vilsbøll, A. Junker, S. Sachs, K. Stemmer, T. D. Müller, M. H. Tschöp, S. M. Hofmann, and M. Mann. "Plasma Proteome Profiling Discovers Novel Proteins Associated with Non-Alcoholic Fatty Liver Disease." Mol Syst Biol 15, no. 3 (Mar 1 2019): e8793. http://dx.doi.org/10.15252/msb.20188793.
Norheim, F., Y. Hasin-Brumshtein, L. Vergnes, K. Chella Krishnan, C. Pan, M. M. Seldin, S. T. Hui, M. Mehrabian, Z. Zhou, S. Gupta, B. W. Parks, A. Walch, K. Reue, S. M. Hofmann, A. P. Arnold, and A. J. Lusis. "Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits." Cell Metab 29, no. 4 (Apr 2 2019): 932-49.e4. http://dx.doi.org/10.1016/j.cmet.2018.12.013.
Sachs, S., A. Bastidas-Ponce, S. Tritschler, M. Bakhti, A. Böttcher, M. A. Sánchez-Garrido, M. Tarquis-Medina, M. Kleinert, K. Fischer, S. Jall, A. Harger, E. Bader, S. Roscioni, S. Ussar, A. Feuchtinger, B. Yesildag, A. Neelakandhan, C. B. Jensen, M. Cornu, B. Yang, B. Finan, R. D. DiMarchi, M. H. Tschöp, F. J. Theis, S. M. Hofmann, T. D. Müller, and H. Lickert. "Targeted Pharmacological Therapy Restores Β-Cell Function for Diabetes Remission." Nat Metab 2, no. 2 (Feb 2020): 192-209. http://dx.doi.org/10.1038/s42255-020-0171-3.
Sachs, S., L. Niu, P. Geyer, S. Jall, M. Kleinert, A. Feuchtinger, K. Stemmer, M. Brielmeier, B. Finan, R. D. DiMarchi, M. H. Tschöp, N. Wewer Albrechtsen, M. Mann, T. D. Müller, and S. M. Hofmann. "Plasma Proteome Profiles Treatment Efficacy of Incretin Dual Agonism in Diet-Induced Obese Female and Male Mice." Diabetes Obes Metab 23, no. 1 (Jan 2021): 195-207. http://dx.doi.org/10.1111/dom.14215.
Sachs, S., S. Zarini, D. E. Kahn, K. A. Harrison, L. Perreault, T. Phang, S. A. Newsom, A. Strauss, A. Kerege, J. A. Schoen, D. H. Bessesen, T. Schwarzmayr, E. Graf, D. Lutter, J. Krumsiek, S. M. Hofmann, and B. C. Bergman. "Intermuscular Adipose Tissue Directly Modulates Skeletal Muscle Insulin Sensitivity in Humans." Am J Physiol Endocrinol Metab 316, no. 5 (May 1 2019): E866-e79. http://dx.doi.org/10.1152/ajpendo.00243.2018.