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Our Projects

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Project 1

A novel toolkit for motion-robust multi-parametric quantitative Magnetic Resonance Imaging of human adipose tissue

Dies ist eine Projektbeschreibung. Erklären Sie in kurzen Worten den Hintergrund Ihrer Arbeit. Um Loszulegen, klicken Sie auf ‚‚Text bearbeiten‘‘ oder doppelklicken Sie auf das Textfeld.

Project 2

Label-free imaging of metabolic parameters in animals and humans

With a newly designed MSOT scanner that reaches deeper we will measure tissue bioenergetics and lipid profiles in-vivo, characterize metabotypes, and identify novel imaging-based biomarkers. Our aim is to gain new understanding of metabolic diseases which allows for the application of novel diagnostic and theranostic approaches. In addition, we will provide our project partners with a suitable toolbox to obtain the most meaningful MSOT derived metabolic information.

Image by Misael Moreno
Image by ThisisEngineering RAEng

Project 3

Label-free imaging of metabolic parameters in animals and humans

MiROM-based optoacoustic imaging of inguinal white adipose tissue (iWAT). Lipids are visualized in red; amide II bands of proteins are visualized in green. The characteristic lymph node of iWAT was captured in the right upper corner. Both, adipocytes with large lipid droplets and low protein content and adipocytes with high protein content and smaller lipid droplets can be discovered.

Project 4

Non-traditional biomarkers in intermuscular adipose tissue to monitor metabolic health

Dies ist eine Projektbeschreibung. Erklären Sie in kurzen Worten den Hintergrund Ihrer Arbeit. Um Loszulegen, klicken Sie auf ‚‚Text bearbeiten‘‘ oder doppelklicken Sie auf das Textfeld.

Image by FLY:D
InfraredK.PNG

Project 5

Meal-associated metabolic responses in brown adipose tissue and skeletal muscle related to weight loss

We apply non-invasive imaging technologies to investigate meal- and cold induced metabolic responses in brown adipose tissue and skeletal muscle. People with obesity will be compared to lean controls, studying the effects of exercise and caloric restriction. In this context we will analyze the role of the gut hormone secretin as an endocrine activator of metabolism.